Brain development during a child’s first five years forms the basis for lifelong learning and physical health, making enriched environments critical to success. Hospitals and clinics represent an untapped opportunity to contribute in this pivotal period. From a newborn’s first day of life to the many subsequent well-child and sick-care visits, the health care milieu offers knowledge, equipment, and training that nurtures healthy children. Can pediatric care be reimagined to spark brain-building interactions, promote executive function, and strengthen parent/child relationships? What do the new models look like?