Pharmaceutical advances are expanding, with some exciting new drugs already on the market and others ready to emerge from the pipeline. These therapeutics offer fresh hope for combatting perilous infections, such as multi-drug resistant tuberculosis, and neglected tropical diseases, which affect more than one billion people every year. But it takes more than product development to reduce these global threats; it also requires policies to scale up distribution and reach the hardest to serve. What cutting-edge therapies are being added to the global arsenal? How do we put them in the right hands at the right price?