CRISPR 2.0, the Next Generation

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History was made this year when the first FDA-approved CRISPR-based gene editing therapy became available to patients, designed to cure sickle cell anemia. That represents ground-breaking progress, but the treatment involves a months-long ordeal with often-brutal side effects and it is hugely expensive. With dozens of CRISPR therapeutics in the second phase of human trials, hopes run high that next-generation approaches will be easier and cheaper to deliver and more patient friendly. The payoff could be major progress in treating blood disorders, cardiovascular disease, cancer, and infectious diseases.

  • 2024 Health

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