More than one-third of the world’s girls and women have experienced some form of violence in their lives, leading the World Health Organization to highlight “a global health problem of epidemic proportions.” In this year of unprecedented attention to women’s safety, we are increasingly aware of their vulnerability to sexual violation, trafficking and other forms of abuse. Ending gender-based violence and human trafficking requires ending the culture of complicity and impunity, empowering women, reforming legal systems, and securing more effective responses from the health and social service systems. Will we make those commitments?