Nothing demonstrates that health is an industry ripe for growth and change more clearly than the enthusiastic participation of venture capitalists. Far more than in the past, they are committing resources to seed start-up operations, not only in artificial intelligence and data science, but also in the life sciences and health-related services and delivery systems. Recognizing the innovations being fueled by scientific breakthroughs, they are eagerly seeking opportunities to enhance and extend life – and to generate profits along the way. How do venture capitalists decide where to place their bets, and what is likely to win big in the coming years? Does health equity factor into their decision making?