Technology is transforming how we provide medical care, improve diagnostics, share information, and extend the reach of public health. From disposable syringes that deliver a calibrated dose of medicine before self-destructing to 3-D printers that recreate the facial structures of combat-injured veterans, seemingly intractable problems are being met with cutting-edge solutions. Sheets laden with bacteria-destroying nanoparticles are being used as water filters, cell phones are turning into microscopes, the optical signature of cancer cells is being outed, and one’s own immune system is being used to fight cancer. How will technology change health and health care? What else is on the horizon?