There is nothing new about globalization. A catchphrase today, trade and the drive for economic growth and opportunity have defined global economic integration for centuries (consider the Roman Empire and the Silk Route). But the complexity of these vast movements of goods, services, technology innovation, and information, has riven public sentiment in the 21st century. While most will argue for the kinds of economic growth and prosperity that the products of globalization have delivered, tensions are fierce around their impacts on jobs, workers, and income stagnation. We now find ourselves in a perfect storm of economic, political, environmental, and cultural forces which are creating new frictions at home and abroad as the nature and quality of jobs, income, and education shift. How do we balance the needs of income growth and job creation with our insatiable demand for low-priced goods and services? What makes for prudent policy in an age of “America First”?